Search Results - jolene bowers

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Assays for the detection of Enterovirus D68
Researchers at TGen have developed assays for the detection of Enterovirus D68 (EV-D68) in complex patient samples. Both PCR and amplicon sequencing assays rapidly diagnose patients with EV-D68 respiratory illness, and can be used to assess a patient’s risk of acute flaccid myelitis (AFM) and potentially diagnose AFM. The assays can additionally...
Published: 3/22/2019   |   Inventor(s): David Engelthaler, Jolene Bowers
Keywords(s):  
Category(s): Diagnostics
Methods for Detecting and Differentiating Burkholderia pseudomallei and Burkholderia mallei with a Single Probe DNA SNP Assay
Researchers at TGen and Northern Arizona University (NAU) have developed a method for detecting Burkholderia pseudomallei and Burkholderia mallei from a single DNA SNP in a sample using Taqman SNP dual-probe allelic discrimination real-time PCR assay. This assay provides a single-step, single reaction for identifying and differentiating between B....
Published: 2/6/2019   |   Inventor(s): Jolene Bowers, David Engelthaler, Paul Keim
Keywords(s):  
Category(s): Diagnostics
Allelic Discrimination Assays for MRSA Strains
Researchers at TGen and Northern Arizona University (NAU) have developed methods to rapidly identify and differentiate Methicillin-Resistant Staphylococcus aureus (MRSA) strains using real-time PCR assays. These allelic discrimination assays target SNPs to distinguish the clinically important MRSA strains USA100, USA300, USA 600, and other MRSA strains,...
Published: 2/1/2019   |   Inventor(s): Paul Keim, Elizabeth Driebe, David Engelthaler, Jolene Bowers
Keywords(s):  
Category(s): Diagnostics
Assays for Antibiotic Resistance Gene Detection in Staphylococcus Strains
Researchers at TGen and Northern Arizona University (NAU) have developed a multiplex real-time PCR profiling assay for detecting antibiotic resistance-conferring genes in Staphylococcus strains. The multiplex assay determines the susceptibility of strains such as MRSA, MSSA, MRSE, and MSSE to antibiotics including aminoglycoside, vancomycin, penicillin,...
Published: 2/1/2019   |   Inventor(s): Paul Keim, Elizabeth Driebe, David Engelthaler, Jolene Bowers
Keywords(s):  
Category(s): Diagnostics
Repurposed Drugs for the Treatment of Fungal Infections Caused by Coccidioides
Researchers at TGen and Northern Arizona University (NAU) have developed an effective treatment for fungal infections caused by Coccidioides including the Valley Fever-causing species: Coccidioides immitis and Coccidioides posadasii in humans and companion animals (particularly canines). Repurposed drugs originally developed to inhibit hormone uptake...
Published: 1/30/2019   |   Inventor(s): David Engelthaler, Elizabeth Driebe, Hongwei "Holly" Yin, Michael Valentine, Donald Chow, Jolene Bowers, Paul Keim
Keywords(s): Pathogens, Veterinary Medicine
Category(s): Therapeutics
Amplicon Sequencing Analysis Pipeline (ASAP)
TGen and Northern Arizona University have developed a high-throughput bioinformatics tool for interpreting the significance of alignment data from amplicon sequencing. Amplicon sequencing allows for rapid, cost-effective, highly multiplexed, and accurate detection of numerous clinically important targets directly in clinical samples. The Amplicon...
Published: 1/24/2019   |   Inventor(s): Darrin Lemmer, Jolene Bowers, Elizabeth Driebe, Erin Kelley, David Engelthaler, Paul Keim
Keywords(s):  
Category(s): Computer Methods, Diagnostics
Amplicon sequencing technology for the detection of Lyme disease and other infectious diseases
Researchers at TGen and Northern Arizona University have developed technology to increase the speed and accuracy of diagnosing and assessing Lyme Disease and other infectious diseases. This amplicon sequencing technology for Lyme Disease and other infectious diseases can be used commercially in a rapid and accurate fashion:• as a diagnostic...
Published: 7/17/2018   |   Inventor(s): Elizabeth Driebe, Paul Keim, David Engelthaler, Jolene Bowers, Nathan Nieto
Keywords(s):  
Category(s): Diagnostics
Rapid typing and subtyping of Staphylococcus aureus clonal complex 8 (CC8) strains
Researchers at TGen and the United States Centers Disease Control and Prevention (CDC) have collaboratively developed a panel of assays for rapidly and consistently typing Staphylococcus aureus strains, and subtyping the strains within clonal complex 8 (CC8). The developed technology is an improvement over previously used typing methods and can be...
Published: 7/11/2018   |   Inventor(s): Elizabeth Driebe, Jolene Bowers, David Engelthaler, Paul Keim, Brandi Limbago, James Rasheed, Linda Mcdougal, Valerie Albrecht
Keywords(s):  
Category(s): Diagnostics
KlebSeq: amplicon sequencing screening tool for Klebsiella species.
Researchers at TGen and Northern Arizona University have developed a highly informative screening tool called KlebSeq that detects Klebsiella species and identifies clinically important strains and characteristics using highly multiplexed amplicon sequencing without a live culturing step. KlebSeq comprises 5 species identification assays, 35 strain...
Published: 8/17/2017   |   Inventor(s): Jolene Bowers, Darrin Lemmer, Elizabeth Driebe, David Engelthaler, Paul Keim
Keywords(s):  
Category(s): Diagnostics
Allelic discrimination assays for important Klebsiella pneumoniae strains
Researchers at TGen and Northern Arizona University have identified robust genomic signatures unique to certain particularly virulent strains of Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae and have designed molecular assays to detect K. pneumoniae and distinguish those strains. Both assays show 100% sensitivity and specificity,...
Published: 8/17/2017   |   Inventor(s): Jolene Bowers, Paul Keim, David Engelthaler, Elizabeth Driebe
Keywords(s):  
Category(s): Diagnostics
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