Search Results - patrick pirrotte

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Molecular Assay for Diagnosing and Prognosing Esophageal Adenocarcinoma
Through a collaboration between TGen and Dignity Health, researchers have developed an assay for early detection and monitoring of Esophageal Adenocarcinoma (EA), which differentiates Metaplasia from Dysplasia patients and monitors progression of EA . The identified panel of markers can be monitored non-invasively for uptake and release changes through...
Published: 4/9/2019   |   Inventor(s): Landon Inge, Timothy Whitsett, Patrick Pirrotte, Khyatiben (Khyati) Pathak
Category(s): Diagnostics
Method of Detecting Low Abundance Circulating Extracellular Vesicles
Researchers at TGen have developed an improved method of detecting circulating extracellular vesicles (EVs) in low abundance from a patient blood sample. These detected EVs may be used as biomarkers for cancer and other diseases in an early and non-invasive detection method. For example, this method can be used for the detection of breast cancer specific...
Published: 3/22/2019   |   Inventor(s): Patrick Pirrotte
Category(s): Proteomics
Neural Network Approach to Matching of Mass Spectral Data
Researchers as TGen have developed methods and algorithms to improve the yield of identifiable protein sequences from mass spectrometry data. Using a Convolutional Neural Network (CNN) approach, proteins, peptides, and other small molecules can be classified and identified from mass spectrometry data with additional confidence in a high throughput...
Published: 3/22/2019   |   Inventor(s): Patrick Pirrotte, Gil Speyer, Ritin Sharma, Krystine Garcia-Mansfield
Category(s): Proteomics, Computer Methods
Methods for Detecting and Treating Coccidioides Infections
Researchers at TGen have developed methods for detecting and treating Coccidioides infections (also known as Valley Fever) using novel proteins. Using these proteins as biomarkers, clinicians can detect this fungal infection from patient samples early in the infection cycle (within the first five days of infection) and implement a targeted treatment,...
Published: 1/29/2019   |   Inventor(s): Bridget Barker, Patrick Pirrotte
Category(s): Diagnostics