Search Results - Genomics/Genetics

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Screening and Treatment Methods for Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT)
Researchers at TGen, in collaboration with the University of British Columbia, have developed methods and compositions for screening for Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT) in a patient based on the genomic profile of a biological sample to enable earlier diagnosis and more effective treatment than is currently available for...
Published: 3/26/2019   |   Inventor(s): Jeffrey Trent, Pilar Ramos, William Hendricks, Anthony "Tony" Karnezis, David Huntsman, David Craig, Hongwei "Holly" Yin, Yemin Wang
Keywords(s): Small Cell Carcinoma, Solid Tumors
Category(s): Genomics/Genetics
MAMA Real-Time PCR Assay Panel for Genotyping Cyrptococcus gattii
Researchers at TGen and Northern Arizona University (NAU) have developed methods for genotyping Cryptococcus gattii using a mismatch amplification mutation assay (MAMA) real-time PCR assay panel. This assay panel provides a rapid method for genotyping of C. gattii molecular types VGI-VGIV and the dominate North American VGII molecular subtypes VGIIa-c...
Published: 1/30/2019   |   Inventor(s): David Engelthaler, Elizabeth Driebe, Erin Kelley, Paul Keim
Keywords(s): Pathogens
Category(s): Genomics/Genetics, Diagnostics
Universal Spike-Ins for ctDNA Assays
Researchers at TGen have developed a method for validating patient-specific oligonucleotides using spike-in sequences. This method involves introducing spike-in oligo sequences to cosynthesized synthesis-control oligonucleotides and patient-specific oligonucleotides. Reading out the counts of spike-in sequences determines the dose-response characteristics...
Published: 8/17/2017   |   Inventor(s): Tim Mcdaniel, Muhammed Murtaza
Category(s): Diagnostics, Genomics/Genetics
A Universal Multiplex Indexing strategy for Next Generation Amplicon Sequencing (UMINGAS)
Researchers at TGen and Northern Arizona University have developed a Next Generation universal indexing amplicon sequencing strategy that can be used to amplify multiple genomic regions from a DNA sample simultaneously in a single reaction. This method uses a set of common indexed oligonucleotides with a Universal Tail (UT) sequence to quickly and efficiently...
Published: 8/17/2017   |   Inventor(s): James Schupp, Rebecca Colman, David Engelthaler, John Gillece, Nathan Hicks, Paul Keim
Category(s): Genomics/Genetics, Process/Procedures