Search Results - gary flynn

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Methods for identification of compounds capable of selectively eliminating cancer cells with specific loss-of-function alterations
Summary of the InventionResearchers at TGen have patented a method for identifying molecules that reduce viability of cancer cells with a specific pattern of a loss-of-function genetic alteration. These molecules are identified by creating a matched pair of isogenic cell lines that differ only by a siRNA "knock down" of a single DPC4 gene. The matched...
Published: 8/17/2017   |   Inventor(s): Haiyong Han, Daniel Von Hoff, Hong Wang, Gary Flynn
Category(s): Therapeutics